Thank you to all the students who entered projects into the fair this year, the teachers and mentors who supported them, the judges who devoted hours of their time to our students’ presentations, and the sponsors who provided some incredible prizes for our winning projects! We couldn't do this without your creative and innovative ideas.
First place winners qualify to enter ISEF Regeneron International Science and Engineering Fair.
All first, second, and third place winners and honorable mention winners qualify to enter the Massachusetts Science and Engineering Fair (MSEF).
Winners and participating schools will be contacted via email with details on how to register for these fairs. All participants will receive feedback from the judges via their contact teacher.
Congratulations to all the winners!
Region 2 Massachusetts ISEF Delegate
Kelly Mills
The Effect of a Natural and Artificial Yellow Dye on Drosophila Populations and Preference Wachusett Regional High School
Sanofi First Place Award
Harit Sree Charan Suraparaju
From Pollution to Power: Testing Tin-Copper Nanoflowers to Turn CO2 into Formate Grafton High School
First Place Awards
Sahasra Charkam
Parental Pharmacological Modulation of Serotonergic Signaling in C. elegans to analyze hereditary suicide
Massachusetts Academy of Math and Science at WPI
Atharv Joshi
Neuroprotective Effects of Insulin Signaling Modulation in an Alzheimer’s Model
Massachusetts Academy of Math and Science at WPI
Second Place Awards
Anish Gupta
Stopping Stones in Their Tracks: A Comparative In-Vitro Analysis of Natural Inhibitors of Calcium-Oxalate Kidney Stone Formation
Shrewsbury High School
Chenghao Xu
Self-Assembling Modular Robots Enabled by an Articulated Multi-Axis Connector
Massachusetts Academy of Math and Science at WPI
Daniel Korkin
Repurposing FDA Approved Drugs to Fight Neglected Tropical Diseases Using Deep Learning
Westborough High School
Ryan Prendergast
Developing a Mobile Thermal Disposal System for On-Site Construction Wood Waste
Massachusetts Academy of Math and Science at WPI
Third Place Awards
Sanvi Venkayala
Designing a Robot to Measure Soil Hydrophobicity and Optimize Tilling for Hydration
Massachusetts Academy of Math and Science at WPI
William Zhang
From Material to Intelligence: Using Conductive Hydrogels as Smart Skin for Robotic Devices
Shrewsbury High School
Suhrit Ghosh
Fusion-Based Driver State Monitoring: A Multimodal Approach to Drowsiness Mitigation
Massachusetts Academy of Math and Science at WPI
Arjun Mehta and Sahaj Pogula
How does applying a weak electrical force to the Blood-Brain Barrier system make drug delivery more efficient and sufficient?
Hopkinton High School
Neha Nagireddy
ENDO-EC: An Automated Early Esophageal Cancer Detection System via Image Classification and Lesion Segmentation
Shrewsbury High School
Tanay Apte, Varvara Karenski and Mihir Jain
Optimizing Collector Electrode Geometry for Electrohydrodynamic Propulsion Systems
Ashland High School
Michelle Xu
A Severity-Aware Reinforcement Learning System for Optimizing Abdominal Hemorrhage Resuscitation in Physiological Simulation
The Bromfield School
Vaibhav Vinodhkumar
Aerodynamic Optimization of a Bio-Inspired Autorotating Airdrop System: Reducing Landing Error and Impact Velocity
Shrewsbury High School
Aishani Ghosh
Modeling Annihilator to Sensitizer Ratios for Optimal Light Intensity in TTA Upconversion
Massachusetts Academy of Math and Science at WPI
Sahana Chaubal
Investigation of local drinking waters from PFAS-flagged sources reduces lettuce seed germination rate and early or late root/shoot growth compared with municipal and distilled water controls
Worcester Academy
Miles Wilander
The Effect of Activated Carbon on the Heart Rate and Daphnia magna Affected by Glyphosate and 2, 4-D
Wachusett Regional High School
Megan Jeffcoat
Modeling Celiac Immune Activity in C. elegans
Wachusett Regional High School
Ananth Gomatam
Researching the Effects of Indian Carnatic Music on the Behavior of Drosophila melanogaster in an Autism Spectrum Disorder Model
Massachusetts Academy of Math and Science at WPI
Honorable Mentions
Lucia Cranson
The Effect of Glow-in-the-Dark Microplastics on the Growth and Fluorescence of Hydroponically Grown Mint Plants
Wachusett Regional High School
Annie Li
Sustainable Sips: Engineering and Experimental Evaluation of Biodegradable Straw Formulations
Shrewsbury High School
Nirelis Aponte-Garcia
Journey to an Unforgettable Future: The Effects of Lithium Nitrate on Drosophila Learning and Memory
Wachusett Regional High School
Ishan Kasam
A Multi-Fidelity Surrogate-Based Control Framework for Continuously Variable Deployable Vortex Generators
Massachusetts Academy of Math and Science at WPI
Anwita Wadekar
Beyond Food and Fitness: Highlighting the Role of Adverse Childhood Experiences in Youth Obesity
Worcester Academy
Fariba Khan
From Detection to Prescription: A Frugal, On-Device Multimodal AI System for Real-Time Plant Disease Diagnosis and Management
Lincoln-Sudbury Regional High School
Parnitha Karapakula
The Effects of Transgenerational Epilepsy on Dementia Pathology in C. elegans
Massachusetts Academy of Math and Science at WPI
Anushka Singh, Lauren Piel and Navadha Padliya
Testing and Developing a Reliable Enzyme Encapsulation System for β-Galactosidase
Grafton High School
Samad Udaipurwala
Functional Analysis of Attenuated Amyloid-β Neurotoxicity via Pan-Neuronal Hsp104 Co-Expression Mediated by QUAS/57C10 and GAL4/UAS in Drosophila melanogaster
Shrewsbury High School
Helen Taylor
The Impact of Different Modes of News Media Consumption on Extremist Political Beliefs
Bancroft School
Vivienne Liedtke
When Seeing Overrides Feeling: How Virtual Reality Influences Object Recognition and Perception
Blackstone Valley Regional Vocational Technical High School
Ryan Gupta
AquaIntel
Grafton High School
Jayaratna Deshamouni
Novel Programmable Metal-Organic Frameworks Synthesis for Airborne Neurotropic Viruses and Antiviral Immune Pathogenic Resistance in Caenorhabditis elegans using Vitelline Membranes
Shrewsbury High School
Meghna Nambiar
Evaluating Machine Learning Models for Predicting Ciprofloxacin Resistance in Escherichia coli using Genomic Features
The Bromfield School
Kiley Kruger
The Effect of Algae Preventatives on the Propagation of Algae
Wachusett Regional High School
Yinhong Qian
Inflatable soft wearable knee joint rehabilitation device
Worcester Academy
Vikram Hiranandani
Acoustic On-Demand Fishing Gear Release System
Westborough High School
Pahlaj Sharma
Kinetic Energy Harvester to Power Small Devices
Hopkinton High School
Anna Mahoney
A Recipe for Success: The Effect of Variation in Bioplastics Recipes on the Tensile Strength of the Bioplastics
Wachusett Regional High School
Puneeth Nunna
Piezoelectric Energy Harvesting for Next-Generation Aircraft Systems
Shrewsbury High School
Kaushik Satheesh Kumar
Analyzing Packet Transmissions In Low Power Wide Access Networks to identify zero-day Denial-of-Service Attacks using Zero-Shot Techniques
Shrewsbury High School
Swara Patkar, Samanvitha Vangala and Nitya Sunku
Recovery of Dialysis Tubing After Heat Stress
Hopkinton High School
Ritesh Kumar Tondepu, Krishiv Jayaswal and Lokesh Katra
Optimization of a Low-Cost Prosthetic Hand
Grafton High School
Arjun Mohandass
Utilizing Combined Darrieus and Savonius Vertical-Axis Wind Turbine (VAWT) Integrated Traffic Barriers to Recover Untapped Wind Energy Generated by Major Roadways to Improve Conventional Renewable Energy Systems
Shrewsbury High School
Dhanusha Ramadas
A Low-Cost Edge Sweat Sensor That Audibly Alerts Athletes of Rising Dehydration Risk
Westborough High School
Local Sponsored Awards
Blackstone River Valley National Historical Park Environmental Sustainability Award
Arjun Mohandass
Utilizing Combined Darrieus and Savonius Vertical-Axis Wind Turbine (VAWT) Integrated Traffic Barriers to Recover Untapped Wind Energy Generated by Major Roadways to Improve Conventional Renewable Energy Systems
Shrewsbury High School
EARTH ltd. Conservation and Stewardship Award
Sahana Chaubal
Investigation of local drinking waters from PFAS-flagged sources reduces lettuce seed germination rate and early or late root/shoot growth compared with municipal and distilled water controls
Worcester Academy
EcoTarium Museum-Ready Science Awards
Mia Zhao
Edge AI based Multimodal Detection of Health-related Emergencies in a Household Environment
Westborough High School
Vivienne Liedtke
When Seeing Overrides Feeling: How Virtual Reality Influences Object Recognition and Perception
Blackstone Valley Regional Vocational Technical High School
The Hiatt School of Psychology at Clark University Award for Outstanding Project on Psychology and Human Behavior
Anwita Wadekar
Beyond Food and Fitness: Highlighting the Role of Adverse Childhood Experiences in Youth Obesity
Worcester Academy
The Mass Audubon Environmental Research Award
Miles Wilander
The Effect of Activated Carbon on the Heart Rate and Daphnia magna Affected by Glyphosate and 2, 4-D
Wachusett Regional High School
MBI Future Innovator Award
Atharv Joshi
Neuroprotective Effects of Insulin Signaling Modulation in an Alzheimer’s Model
Massachusetts Academy of Math and Science at WPI
New England Botanic Garden Plant Science & Sustainability
Britha Abunga, Anna Platek, Evan St. George
Cracking the Code: Enhancing Fruit Life by Identifying the Enemies of Freshness
Blackstone Valley Regional Vocational Technical High School
WooSox Roberto the Rocket Award
Ryan Prendergast
Developing a Mobile Thermal Disposal System for On-Site Construction Wood Waste
Massachusetts Academy of Math and Science at WPI
Woo! Science Community Impact Awards
First: Viviana Barboza
The Role of Personality and Noise in Short-Term Memory Retention
Bancroft School
Second: Sullivan McCarthy, Vinesh Kanagavel Chithra
Robotic Medication and Cognitive-Assessment App to Enhance Memory Retention in Alzheimer’s Patients
Grafton High School
Third: Swara Patkar, Samanvitha Vangala, Nitya Sunku
Renal Recovery by Recooling: A Dialysis Representation
Hopkinton High School
Honorable Mention: Arya Patel, Rielyn Phoenix
Blocking the Breakdown
Grafton High School
Worcester Regional Chamber of Commerce Emerging Community Leadership in Business & Innovation Award
Anjan Bharath Reddy Lakkadi
Reducing Recycling Contamination Through AI-Powered Waste Classification: Development of an Automated Smart Recycling System
Milford High School
WRSEF Special Awards
Perseverance in Scientific Inquiry Award
Joseph Cordero & Kavin Adhav Sivadhaya
Improving Accelerative Efficiency of Solar Sails
Grafton High School
Rising Researcher Award
Puneeth Nunna
Piezoelectric Energy Harvesting for Next-Generation Aircraft Systems
Shrewsbury High School
Excellence in Scientific Communication Award
Arushi Vora
Using Senolytics to Rescue Cognitive Function in an Alzheimer’s Disease Mouse Model Through Selective Cell-Type Targeting
Westborough High School
Student’s Choice Award
Parnitha Karapakula
The Effects of Transgenerational Epilepsy on Dementia Pathology in C. elegans
Massachusetts Academy of Math and Science at WPI
Outstanding Mentor in Scientific Inquiry Award
Kevin Crowthers
Mass Academy
SFS Special Awards
American Psychological Association Award for Achievement in Research in Psychological Science
Michelle Liu
Detection of Alzheimer's Disease and Related Dementia (ADRD) and Cognitive Impairment: Impacts and supports for patient and society
Algonquin Regional High School
NASA Earth System Science Project Award
Sahana Chaubal
Investigation of local drinking waters from PFAS-flagged sources reduces lettuce seed germination rate and early or late root/shoot growth compared with municipal and distilled water controls
Worcester Academy
United States Air Force Certificate of Achievement
Meghna Nambiar
Evaluating Machine Learning Models for Predicting Ciprofloxacin Resistance in Escherichia coli using Genomic Features
The Bromfield School
Pahlaj Sharma
Kinetic Energy Harvester to Power Small Devices
Hopkinton High School
Shengtao (Alex) Ding
LLM-Driven Text Signals in Multi-Round Prediction Markets: Bayesian Updating, Fractional-Kelly Betting, and Robustness Evaluation
Worcester Academy
Aisha Ali
Computational Model for Early Prediction of Neurological Risk in Silent Hypoxia
The Greater Commonwealth Virtual School
United States Metric Association Science Fair Award for the Best Use of the International System of Units and MCTA
Aishani Ghosh
Modeling Annihilator to Sensitizer Ratios for Optimal Light Intensity in TTA Upconversion
Massachusetts Academy of Math and Science at WPI
The Yale Science & Engineering Association Most Outstanding Exhibit in Science, Technology, Engineering, and Mathematics
Naaisha Agarwal
Using Deep Learning Model to Predict Individual Health Outcomes Due to Migration
Massachusetts Academy of Math and Science at WPI
Ricoh USA Sustainable Development Award
Noah Balon
Exploring Sustainable Agriculture through Soil Carbon Sequestration
Blackstone Valley Regional Vocational Technical High School
NOAA Pulse of the Planet Award
Lumen Zhang, Lindsay Xie and Hareesh Krishnasamy
Simulating Coastal Ecosystems: The Impact of pH, Salinity, and Nutrients on Calcium Carbonate Dissolution
Hopkinton High School
AMD Engineering Excellence Award
Chenghao Xu
Self-Assembling Modular Robots Enabled by an Articulated Multi-Axis Connector
Massachusetts Academy of Math and Science at WPI
Mathematics & Computing Excellence Award
Daniel Korkin
Repurposing FDA Approved Drugs to Fight Neglected Tropical Diseases Using Deep Learning
Westborough High School
Alnylam Bioscience Excellence Awards
Arjun Mehta and Sahaj Pogula
How does applying a weak electrical force to the Blood-Brain Barrier system make drug delivery more efficient and sufficient?
Hopkinton High School
Chemistry Excellence Award
Anish Gupta
Stopping Stones in Their Tracks: A Comparative In-Vitro Analysis of Natural Inhibitors of Calcium-Oxalate Kidney Stone Formation
Shrewsbury High School
Natural Science Excellence Award
Ryan Prendergast
Developing a Mobile Thermal Disposal System for On-Site Construction Wood Waste
Massachusetts Academy of Math and Science at WPI
Behavioral and Social Sciences Excellence Award
Ananth Gomatam
Researching the Effects of Indian Carnatic Music on the Behavior of Drosophila melanogaster in an Autism Spectrum Disorder Model
Massachusetts Academy of Math and Science at WPI
MLSC Trailblazer Award
Zongyuan Jin
Using Colchicine to Produce Polyploid Plants to Increase the Quality of Rose
Worcester Academy
WRSEF 2025-2026 Logo Design Award
Ryan Prendergast
Massachusetts Academy of Math and Science at WPI
Worcester Polytechnic Institute Developing Program Award
Milford High School