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Thank you to all the students who entered projects into the fair this year, the teachers and mentors who supported them, and the judges who devoted hours of their time to our students’ presentations! We couldn't do this without your creative and innovative ideas. Also, a great big thank you to the sponsors and committee members for making the fair possible.
First place winners qualify to enter ISEF Regeneron International Science and Engineering Fair.
All first, second, and third place winners and honorable mention winners qualify to enter the Massachusetts Science and Engineering Fair (MSEF).
Winners and participating schools will be contacted via email with details on how to register for these fairs. All participants will receive feedback from the judges via their contact teacher.
Congratulations to all the winners!
Grand Prize Award Winner & Region II Massachusetts ISEF Delegate
Jayaratna Deshamouni
Shrewsbury High School
Synergistic and Individual Optimization of Reproductive Health and Chronic Stress Resistance in Caenorhabditis elegans Using Resveratrol and Astaxanthin
Sanofi First Place Award
Sierra Kelch
Wachusett Regional High School
A New Mechanism of Harmful Plastics: The Effect of G-15 on the Heart Rate of Daphnia magna Exposed to BPA or BPS
First Place Awards
Neha Nagireddy
Shrewsbury High School
AsthmaAssist: An Application that Better Detects and Monitors Asthma Management Through ML and Post-Diagnostic Tools
Farhan Khan
Lincoln-Sudbury Regional High School
Applying Generative Artificial Intelligence to Social Skills Coaching for Neurodivergent Teens
Second Place Awards
Ansh Hiranandani and Yujiang Zhu
Westborough High School
Protected Species Compliance Drone
Heyna Lee
Wachusett Regional High School
The Effect of Spermidine on Male and Female Drosophila Reproduction
Divi Bhaireddy
St. Mark's School
Ayurvedic Treatment as Oral Hygiene Alternatives for the Prevention of Dental Caries
Megan Darmanin
Wachusett Regional High School
The Effect of Red 40 on the Heart Rate of Daphnia
Vaagmi Shukla
Hopkinton High School
Understanding Neurotoxicity: Drosophila Melanogaster as a Model for Memory Loss
David Priefer and Kais Guessab
Hopkinton High School
From Worms to Humans: Developing Acid-Resistant Casing for Novel Alzheimer’s Drug
Third Place Awards
Anjali Daga
Wachusett Regional High School
Effect of Nigella Sativa Oil on Reducing Oxidative Stress
Emma Toohey
Bancroft School
Creating Desiccation-Tolerant (DT) Koshihikari Rice Plants
Adelaide Mims
St. Mark's School
Affects of Probiotic Supplementation on Migraine-Related Reversals in C. elegans
Emilia Graham
Hopkinton High School
Understanding the Immunomodulatory Effects of Echinacea Purpurea on Caenorhabditis elegans
Emily King
Athol High School
Algae-Pumpkin Bioplastic: A Sustainable Alternative to Conventional Plastics
Hannah Cha
St. Mark's School
Effects of GABA Treatment on Locomotive Behavior Recovery in Sleep-Deprived Drosophila Melanogaster
Shengzhen Wang
St. Mark's School
Detection of Black Ice in Autonomous Vehicles Using Inertial Measurement Based Binary Classification Neural Network
Ishana Saroha
Massachusetts Academy of Math and Science at WPI
The Synergistic Effect of Combining Natural Compounds 1,8-cineole (Eucalyptol) and Naringenin with 11 Antibiotics of Different Drug Classes
Arjun Mohandass
Shrewsbury High School
Capturing Carbon Utilizing Portable Units
Sophia Caramanica
Massachusetts Academy of Math and Science at WPI
Orthotic Hand Brace to Improve Range of Motion and Reduce Pain in Low-Functioning Children with Cerebral Palsy
Miyu Hasegawa and Piyusha Majgaonkar
Hopkinton High School
The Effects of Terpene – a Plant Compound – on Reducing Lobaplatin-Induced Neurotoxicity
Anoushka Nair and Dylan Striek
Hopkinton High School
A Translational Spectrophotometric Apparatus for Noninvasive Glucose Monitoring in Type II Diabetics
Honorable Mentions
Vyshnavi Donthabhaktuni
Massachusetts Academy of Math of Science at WPI
Investigating the Neuroprotective Potential of T.Ammi extract on Parkinson’s Disease via Gut-Brain Axis Modulation
Grace Qiu
Massachusetts Academy of Math of Science at WPI
The Impact Music Genres Play on the Behavioral Responses of Drosophila melanogaster
Kushal Patil
Lincoln-Sudbury Regional High School
Computational Modeling of circCOPA-Antibody Complex for Novel Glioblastoma Detection and Therapeutic Applications
Eleanor Chen, Ruby Tran
Worcester Academy
Investigate Solar Activity Through Directional Muon Detectors on a High-Altitude Balloon
Nichelle Thinagar
Shrewsbury High School
Creating a Soft Biomimetic Robotic Snake With an Anisotropically Frictional Skin Design for Rubble Search and Recovery
Vladyslav Mishyn
St. Mark's School
DAL: Drone-Assisted Acoustic Localization System for Human Detection and Rescue in Disaster-Stricken Environments
Noah Proctor
Massachusetts Academy of Math and Science at WPI
Automatic Irrigation Using Soil and Weather Data
Ravena Arun
Massachusetts Academy of Math and Science at WPI
Using Math Modeling to Identify and Correct Gerrymandering
Avani Jain
Massachusetts Academy of Math and Science at WPI
Pathophysiological Disruption of the Endothelial Glycocalyx by Microplastic Contamination
Kaizar Rangwala
Hopkinton High School
Scientific Machine Learning and Photodynamic Therapy for the Prevention, Anticipatation and Mitagtion of Toxic Algae Blooms
Aryan Shah, Simrit Kukreja
Hopkinton High School
Post-transcriptional Regulation of Huntington's Disease: An Antisense Oligonucleotide Therapeutic Strategy for Inhibiting Mutant Exon 1 Expression
Niranjan Nair
Massachusetts Academy of Math and Science at WPI
Using Contrastive Activation Addition to Combat Societal Biases in Language Models
Kelly Mills
Wachusett Regional High School
Glypho-Fate: The Effect of Roundup on Drosophila melanogaster Fertility
Kevin Branda
Grafton High School
Development of a Novel SHERLOCK Diagnostic Assay for Rapid Detection of Borrelia burgdorferi
Adil Siddiqui
Shrewsbury High School
The Effect of Curcumin on Beta-Amyloid Plaques in the Brain
Maria Mishechkina
Massachusetts Academy of Math and Science at WPI
Solar Powered Water Purification Device Utilizing Membrane Distillation Methods
Meena Lakshmanan
Shrewsbury High School
The Effects of Moringa Oleifera and Nigella sativa on Influenza A Virus
Zuming Zhang
Cushing Academy
Skeleton-based Assessment of Dyskinesia in Parkinson’s Disease Using Spatial Temporal Graph Convolutional Networks
Mia Solomon
St. Mark's School
Does Diet Supplementation with Fructooligosaccharides Reduce Motor Symptom Severity in a D. Melanogaster Model of Parkinson's Disease?
Anwita Wadekar
Worcester Academy
Understanding Social Determinants of Disabilities: A Machine Learning Approach
Jianna Bixho
Massachusetts Academy of Math and Science at WPI
Nanoparticle-Based Disruption of Biofilms: A Novel Strategy to Counteract Antibiotic Resistance
WRSEF Special Awards
American Psychological Association Award for Achievement in Research in Psychological Science
Michelle Liu
New England Chinese Information and Networking Association (NECINA) (Andover)
Is it Harmful or Helpful? Examining the Causes and Consequences of Generative AI Usage Among High School Students
NASA Earth System Science Project Award
Jasmine Palit
Algonquin Regional High
SafeSpace
NOAA Pulse of the Planet Award
Noah Proctor
Massachusetts Academy of Math and Science at WPI
Automatic Irrigation Using Soil and Weather Data
Ricoh USA Sustainable Development Award
Emily King
Athol High School
Algae-Pumpkin Bioplastic: A Sustainable Alternative to Conventional Plastics
United States Air Force Certificate of Achievement
Vladyslav Mishyn
St. Mark's School
DAL: Drone-Assisted Acoustic Localization System for Human Detection and Rescue in Disaster-Stricken Environments
Nichelle Thinagar
Shrewsbury High School
Creating a Soft Biomimetic Robotic Snake With an Anisotropically Frictional Skin Design for Rubble Search and Recovery
Emma Toohey
Bancroft School
Creating Desiccation-Tolerant (DT) Koshihikari Rice Plants
Sophia Caramanica
Massachusetts Academy of Math and Science at WPI
Orthotic Hand Brace to Improve Range of Motion and Reduce Pain in Low-Functioning Children with Cerebral Palsy
The Water Environment Federation/Stockholm Junior Water Prize
Siddharth Gowtham
Shrewsbury High School
WATTer Works
The Yale Science & Engineering Association Most Outstanding Exhibit in Science, Technology, Engineering, and Mathematics
Niranjan Nair
Massachusetts Academy of Math and Science at WPI
Using Contrastive Activation Addition to Combat Societal Biases in Language Models
AMD Engineering Excellence Award
Shengzhen Wang
St. Mark's School
Detection of Black Ice in Autonomous Vehicles Using Inertial Measurement Based Binary Classification Neural Network
MITRE Computer Science & Technology Excellence Award
Neha Nagireddy
Shrewsbury High School
AsthmaAssist: An Application that Better Detects and Monitors Asthma Management Through ML and Post-Diagnostic Tools
Alnylam BioScience Excellence Award
Heyna Lee
Wachusett Regional High School
The Effect of Spermidine on Male and Female Drosophila Reproduction
MCTA Chemistry Excellence Award
Arjun Mohandass
Shrewsbury High School
Capturing Carbon Utilizing Portable Units
MLSC Trailblazer Award
Yinhong Qian
Worcester Academy
Omni-Directional Bionic Crab-like Robot for Ocean Pollution Monitoring
WRSEF 2024-2025 Logo Design Award
Grace Qiu - Massachusetts Academy of Math and Science at WPI
Nancy A. Degon Student Research Grant Recipients
Arushi Vora - Westborough High School
Grace Qiu - Massachusetts Academy of Math and Science at WPI
Emma Toohey - Bancroft School
Worcester Polytechnic Institute Developing Program Award
Blackstone Valley High School
Photos from the 2025 WRSEF Fair and Award Ceremony
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